Online: 9 January 2023; Volume 2, Issue 1, No.1 PDF DOWNLOAD
  • Title:
  • Gas Chromatography/Mass Spectrometry (GC/MS) analysis of Heliotropium ovalifolium Forssk. root and aerial part extracts
  • Author:

    Manal A Ibrahim, Hatil Hashim EL-Kamali

  • Author Affiliation:

    Department of Botany, Faculty of Science and Technology, Omdurman Islamic University, Omdurman, Sudan

Abstract
In the history of folk medicine Heliotropium ovalifolium plant used to cure for inflammation, poison bites, skin and nervous disorders. The roots and aerial parts extracted by n-hexane and subjected to analysis using Gas Chromatography/Mass Spectrometry (GC/MS). Various constituents identified. Root extract was identified by abundance of hexadecanoic acid, methyl ester (24.50%), methyl stearate (15.61%), oxiraneoctanoic acid, 3-octyl, methyl ester (12.29%), 9-octadecenoic acid (Z)-, methyl ester (10.17%) and 9,12-Octadecadienoic acid (Z, Z)-, methyl ester (7.29%). While aerial parts extract showed eight alkane compounds which were identified as major constituents (62.89%) out of these compounds was heneicosane which showed high percentage (34.14%) and consider as a bioactive molecule. The present study revealed that the fatty acids in H. ovalifolium may be explored for manufacturing industrial products and pharmaceutical agents.
References
[1] Selvi, F., Bigazzi, M., (2001). Leaf surface and anatomy in Boraginaceae tribe Boragineae with respect to ecology and taxonomy. Flora 196, 269–285.
[2] Kumar, P, Ayyanar,M., Lgnacimuthu, S. (2007). Medicinal plants used by Malasar tribes of Coimbatore district,Tamil Nadu, Indian J. of traditional knowledge. 6(4),579-582.
[3] Mohanraj S, Kulanthaivel P, Subramanian PS, Herz W(1981). Helifoline, a pyrrolizidine alkaloid from Heliotropium ovalifolium, Phytochemistry 20(8), - 1991-1995.
[4] Gurib-Fakim, A. (2006). Heliotropium ovalifolium Forssk. [Internet] Record from PROTA 4U. Schmelzer, G.H. and Gurib-Fakim , A. (Editors). PROTA (Plant Resources of Tropical Africa/, Wageningen, Netherlands.
[5] Guntern A. et al., (2003). Heliotropamide, a novel oxopyrrolidine -3-carboxamide from Heliotropium ovalifolium. J.Nat.Prod. PMID: 14695794.
[6] Guntern A, Ioset J-R, Queiroz EF, Foggin CM, Hostettmann K(2001). Quinones from Heliotropium ovalifolium. Phytochemistry,58(4), 631-635.
[7] Tiwari KP and Masood M. (1977) “Chemical constituents of Heliotropium ovalifolium”. Proceedings of the National Academy of Science (India), Sect. A 47: 72
[8] Kulkarni-Almeida A., et al. (2008) “Novel leads from Heliotropium ovalifolium, 4, 7, 8-trimethoxy-naphthalene-2-carboxylic acid and 6-hydroxy-5, 7-dimethoxy-naphthalene-2 carbaldehyde show specific IL-6 inhibitory activity in THP-1 cells and primary human monocytes”. Phytomedicine 15: 1079-1086
[9] Wang et al. (2012). The powerful applications of polyunsaturated fatty acids in improving the therapeutic efficacy of anticancer drugs. Expert Opin. Drug Deliv.
[10] Ahmad M.S. (1984). An 8-hydroxyoctadeca-cis-11, 14-dienoic acid from Mirabilis jalapa seed oil. Phytochem.J.
[11] Ortsater H (2011). Arachidonic acid fights palmitate: New insights into fatty acid toxicity in β-cells. J. Clin. Sci. 120:179-181.
[12] Isidrov VA, Czyzewska V, Jankowsk M, Bakier S (2011). Determination of royal jelly acid in honey. J. Food Chem. 124:387-391.
[13] Vanitha, V., Vijayakumar S., Nilavukkarasi M, Punitha V. N.,Vidhya E. (2020). Heneicosane—A novel microbicidal bioactive alkane identified from Plumbago zeylanica L. J. Industrial crops and products 154.

Copyright 2018 - 2023 Sanderman Publishing House