Volume 2, Issue 1, No.3 PDF DOWNLOAD
  • Title:
  • Evaluation of interleukin -1 alpha, lipase and vitamin D3 in patients with giardiasis
  • Author:

    Fatima Assad Baker Al-musawy, Murtada Hafedh Hussein

  • Author Affiliation:

    College of Science, Thi-Qar University, Thi-Qar, Iraq

  • Received:Jun.22, 2023
  • Accepted:Jul.7, 2023
  • Published:Jul.25, 2023
Abstract
Background: Giardiasis is one of most gastrointestinal parasite infection around world, affecting all people especially children under age five. Methods: The present research performed from the start of September 2021 to the end of March 2022, (50) blood samples were taken from suspected infected patients with G. lamblia and proved to be infected with the Giardia and (40) blood samples collected from healthy people as a control group. human IL-1A was measured by ELISA technique. The concentration of serum Lipase was measured by dry chemistry in the Fujifilm method, while the level of vitamin D3 was evaluated by Cobas E411 device Results: This study found that the level of interleukin -1 alpha has significantly increased in (p <0.05) in the infected patients with parasite further were the study of biochemical parameters of patients infected with parasite showed increase in concentration of lipase, and decrease in concentration of vitamin D3 in patients when compared to the healthy group. The results also showed that activity of lipase enzyme have been shown to be reduced when G. lamblia incubated with some intestinal parasites in vitro. Conclusions: it is concluded that giardiasis is a significant inflammatory process that results in changes in and vitamin D3lipid metabolism.  
Keywords

Giardiasis, interleukin-1 alpha, vitamin D3, lipase.

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