Observation of effect of different doses of gamma globulin combined with dexamethasone on children with ITP

Journals

Online: 3 November 2022; Volume 1, Issue 1, No.1 PDF DOWNLOAD

Title：
Observation of effect of different doses of gamma globulin combined with dexamethasone on children with ITP
Author：
Chaohui Hou
Author Affiliation：
Shanxi Children’s Hospital, Taiyuan, China

Abstract

Purpose: To observe the clinical efficacy of different doses of gamma globulin combined with dexamethasone in treating children with idiopathic thrombocytopenic purpura (ITP). Methods: 116 children with ITP admitted from 2018 to 2019 were selected as the study objects and randomly divided into the control group and the observation group, with 58 cases in each group. The control group was treated with high-dose gamma globulin combined with dexamethasone, and the observation group was treated with low-dose gamma globulin combined with dexamethasone. The therapeutic effect of the two groups of children and the changes in platelet related indicators before and after treatment were compared. Results: the total effective rate was 82.76% for the observation group and 87.93% for the control group, and there was no statistical difference between the two groups (P>0.05). After treatment, the average levels of PLT, MPV, PDW and PCT in the two groups were higher than those before treatment (P<0.05), and the differences were statistically significant, while the platelet related parameters between the two groups after treatment had no statistical difference (P>0.05). Conclusion: Low-dose gamma globulin combined with dexamethasone has a definite therapeutic effect in the treatment of children with ITP, and the cost is low, so that it is worthy of clinical promotion and application.

References

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