Online: 3 November 2022; Volume 1, Issue 1, No.4 PDF DOWNLOAD
  • Title:
  • Clinical study on humidified high-flow nasal cannula in the treatment of recurrent apnea in premature infants
  • Author:

    Binbin Yi

  • Author Affiliation:

    Hebi People’s Hospital, Hebi, China

Abstract
Purpose: To explore the clinical effect of humidified high-flow nasal cannula (HHFNC) in the treatment of recurrent apnea in premature infants. Methods: 94 premature infants with recurrent apnea were selected and randomly divided into two groups. The observation group was treated with NHFNC, and the control group was treated with nasal continuous positive airway pressure (NCPAP). The clinical effects of the two groups were compared. Results: there was no statistically significant difference in total effective rate, non-invasive assisted ventilation time and oxygen therapy time between the two groups (P>0.05); the start time of breastfeeding and the time to reach full enteral feeding of the observation group were shorter than those of the control group; PaCOand PaOwere compared 24h after treatment; the incidences of feeding intolerance, nasal injury and abdominal distension of the observation group were lower than those of the control group, and the differences were statistically significant (P<0.05). Conclusion: HHFNC treatment of recurrent apnea can improve the patients’ blood gas indicators, shorten the time of non-invasive ventilation, and reduce the incidence of complications. 
References

[1] Cai Yan, Yang Zuming, Wang Sannan, et al. Treatment of severe apnea in premature infants with humidified high-flow nasal cannula [J]. Chinese Pediatric Emergency Medicine, 2014, 21(12):790-794.

[2] Gao Yujian, Liao Liangrong, Wu Xueke, et al. Research progress of neonatal humidified high-flow nasal cannula in the treatment of premature infants with apnea [J]. Hainan Medical Journal, 2016,27(15):2497-2499.

[3] Wang Xuli, Yang Zuming, Gu Danfeng, et al. A semi-randomized controlled study on the treatment of apnea in infants with very low birth weight by warm humidified high-flow nasal cannula [J]. Journal of Clinical Medicine in Practice, 2016,20(7):102-104.

[4] Gao Yujian, Liao Liangrong, Jiang Shaoming, et al. Clinical study on humidified high-flow nasal cannula in the treatment of recurrent apnea in premature infants [J]. Chinese Journal of Neonatology, 2016, 31(6):433437.

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